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Should i adjust advil dosage with antidepressants?



Based on the information provided, it is recommended to consult with a healthcare professional before adjusting Advil (ibuprofen) dosage while taking antidepressants.

According to the drugpatentwatch.com page for Advil, there are no known major interactions between Advil and antidepressants. However, the information on this page should not be used as a substitute for professional medical advice.

The CCJM article discusses the use of nonsteroidal anti-inflammatory drugs (NSAIDs) like Advil in conjunction with selective serotonin reuptake inhibitors (SSRIs) and selective norepinephrine reuptake inhibitors (SNRIs), two common classes of antidepressants. The article states that "the concurrent use of NSAIDs and antidepressants may increase the risk of gastrointestinal, renal, and cardiovascular adverse effects" [${2}].

The NHS page for the antidepressant nortriptyline states that "you should not take ibuprofen (a type of non-steroidal anti-inflammatory drug or NSAID) at the same time as nortriptyline" [${3}].

Therefore, while there may not be major interactions between Advil and antidepressants, it is important to be aware of the potential increased risks of gastrointestinal, renal, and cardiovascular adverse effects. Additionally, some specific antidepressants, such as nortriptyline, should not be taken with Advil. It is always best to consult with a healthcare professional before making any changes to medication regimens.

Sources:

* [Advil Patent Information](https://www.drugpatentwatch.com/p/tradename/ADVIL)
* [CCJM Article on NSAIDs and Antidepressants](https://www.ccjm.org/content/89/1/18)
* [NHS Page on Nortriptyline](https://www.nhs.uk/medicines/nortriptyline/)



Follow-up:   Can antidepressants interact with Advil? Should Advil dosage change with antidepressant use? Is it safe to combine Advil and antidepressants?





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