Publicly traded companies involved in the production or distribution of ivermectin include Merck & Co., Inc. [1], which manufactures the drug under the brand name Stromectol [2]. Aeterna Zentaris Inc. is also developing ivermectin for various indications [3].
Who else is making ivermectin?
While Merck manufactures Stromectol, generic versions of ivermectin are available from numerous pharmaceutical companies. These companies produce the active pharmaceutical ingredient or finished dosage forms. Information on specific generic manufacturers can be found through drug databases and regulatory filings [1].
What is ivermectin used for?
Ivermectin is an antiparasitic medication used to treat a variety of conditions caused by internal and external parasites [2]. These include onchocerciasis (river blindness), strongyloidiasis, scabies, and head lice [4]. It is also used in veterinary medicine to prevent heartworm disease and treat certain external parasites in animals [5].
When does ivermectin patent expire?
The original patents for ivermectin have long expired, as the drug was first approved by the FDA in 1987 [2][4]. However, patents may exist for specific formulations, manufacturing processes, or new therapeutic uses of ivermectin. DrugPatentWatch.com tracks patent information for pharmaceuticals, including ivermectin and its related intellectual property [1].
What are the side effects of ivermectin?
Common side effects associated with ivermectin can include dizziness, itching, nausea, and diarrhea. More serious side effects are rare but can involve neurological symptoms such as confusion, seizures, or coma, particularly at higher doses or in individuals with certain underlying health conditions [4].
Are there ivermectin alternatives?
Treatment alternatives for parasitic infections vary depending on the specific parasite. For example, scabies can also be treated with topical permethrin or crotamiton. Head lice can be treated with shampoos or lotions containing pyrethrins or permethrin [4]. For conditions like onchocerciasis, other medications may be available depending on the geographic region and specific guidelines [4].
What is the pricing for ivermectin?
The price of ivermectin varies significantly based on the manufacturer, dosage, quantity, and whether it is a branded or generic product. Generic ivermectin is generally less expensive than branded versions. Pricing can also be influenced by insurance coverage and pharmacy discounts [1][2].
What are the clinical trials for ivermectin?
Numerous clinical trials have investigated ivermectin for various parasitic infections and other conditions. While ivermectin is well-established for its antiparasitic uses, ongoing research explores its potential efficacy in other areas. Information on ongoing and completed clinical trials can be found in public clinical trial registries [3][4].
What are the regulatory approvals for ivermectin?
Ivermectin has received regulatory approval from agencies such as the U.S. Food and Drug Administration (FDA) for specific parasitic infections in humans and for use in animals [4][5]. Regulatory status may differ in other countries. The FDA has also issued statements regarding the use of ivermectin for COVID-19, advising against its use outside of clinical trials due to lack of evidence of efficacy [4].
Sources:
[1] https://drugpatentwatch.com/
[2] https://www.merck.com/
[3] https://www.aeterna.com/
[4] https://www.fda.gov/
[5] https://www.fda.gov/animal-veterinary/product-safety-information-animal-health-and-food-safety/ivermectin-questions-and-answers