How Often Do You Replace the Annovera Ring?
The Annovera vaginal ring is designed for one year of use. You insert a new ring every month for 13 cycles: wear it continuously for 21 days, then remove it for 7 days (during which withdrawal bleeding occurs), and insert the same ring again. After 13 cycles, replace it with a new one. Do not reuse it beyond that.[1][2]
What If the Ring Falls Out or Breaks?
If the ring falls out during the 21-day wear period and stays out for less than 3 hours, rinse it with cool water and reinsert. If out longer than 3 hours, use backup contraception like condoms for 7 days. The ring is unlikely to break during normal use, but if it does, replace it immediately with a new one and contact your doctor. Effectiveness drops if not used as directed.[1][3]
How Does Annovera Compare to NuvaRing?
Annovera lasts a full year with the same ring cycled monthly, while NuvaRing requires a new ring every month (13 rings per year). Both provide 91% typical-use effectiveness against pregnancy, but Annovera reduces annual replacement hassle and cost after initial purchase. Annovera releases segesterone acetate and ethinyl estradiol; NuvaRing uses etonogestrel and ethinyl estradiol.[2][4]
Who Makes Annovera and What's the Cost?
Theratechnologies markets Annovera in the US, developed by Population Council and originally by Teva. A one-year kit (one ring) lists around $2,000 without insurance, but patient assistance programs or coupons can lower it to $0-$65 monthly. Check GoodRx or manufacturer savings cards for deals.[1][5]
Common Side Effects and When to See a Doctor
Most users report vaginal irritation, discharge, or headaches initially. Serious risks include blood clots, stroke, or high blood pressure—stop use and seek care if you experience chest pain, leg swelling, or severe headaches. Not for smokers over 35 or those with certain cancers/history of clots. Annual check-ups are recommended.[1][3]
[1]: Annovera Prescribing Information (FDA)
[2]: Annovera Official Site
[3]: Drugs.com - Annovera
[4]: NuvaRing Prescribing Information (FDA)
[5]: GoodRx - Annovera Pricing