How do i rotate injection sites for kesimpta?

Why Rotate Injection Sites for Kesimpta?

Kesimpta (ofatumumab) is injected subcutaneously, usually in the thigh, abdomen, or upper arm. Rotating sites prevents skin irritation, lumps, or tissue damage from repeated injections in the same spot.[1]

Recommended Injection Sites

Use these areas, at least 2 inches (5 cm) from the belly button or previous sites:
- Abdomen: Avoid the 2-inch area around the navel.
- Front of thigh: Upper outer part.
- Back of upper arm: Needs a caregiver's help.

Do not inject into moles, bruises, scars, or tender skin.[1][2]

Step-by-Step Rotation Process

1. Plan a map: Divide each area into sections (like a clock face) and track used spots on paper or an app.
   
2. Inject in a new section each time, moving clockwise or systematically.
   
3. Alternate areas weekly: e.g., abdomen (weeks 1-2), thigh (weeks 3-4), arm (weeks 5-6), then repeat.
   
4. Space shots 1-2 inches apart minimum.
   
5. For loading doses (Days 1, 7), use the same area but different spots; for monthly doses (Day 14+), switch areas.
   
   Example weekly schedule for self-injection:
   | Week | Site |
   |------|---------------|
   | 1 | Abdomen |
   | 2 | Thigh |
   | 3 | Upper arm |
   | 4 | Abdomen |
   
   Mark your calendar or use the Kesimpta app reminders.[1]
   
   

Tips to Avoid Common Issues

• Clean skin with alcohol swab; let dry.
  
• Pinch skin, insert needle at 90 degrees, inject slowly over 5-10 seconds.
  
• Rotate even if no irritation appears—prevents long-term problems like lipohypertrophy.
  
• If a site gets red, swollen, or hard, skip it for 1-2 weeks and note for your doctor.
  
  

What If You Miss a Rotation or Get Reactions?

Consult your doctor for persistent issues like infection signs (fever, pus). They may adjust your plan. Full instructions come with the pen and patient brochure.[1][2]

[1]: Kesimpta Prescribing Information (Novartis)
[2]: Kesimpta Patient Instructions for Use