The IUPAC name for clemastine fumarate is 2-[2-[(1R,2S)-1-methyl-2-(4-methylphenyl)ethyl]pyrrolidin-1-yl]ethan-1-ol fumarate. [1]
What is clemastine fumarate used for?
Clemastine fumarate is an antihistamine used to treat symptoms of allergies, such as sneezing, runny nose, itching, and watery eyes. It is also used to treat hives and other skin itching and rashes. [2]
How does clemastine fumarate work?
Clemastine fumarate works by blocking the action of histamine, a substance in the body that causes allergic symptoms. [2]
What are the potential side effects of clemastine fumarate?
Common side effects of clemastine fumarate may include drowsiness, dizziness, dry mouth, and blurred vision. Less common side effects can include confusion, difficulty urinating, and rapid heartbeat. [2]
What is the difference between clemastine and clemastine fumarate?
Clemastine is the active pharmaceutical ingredient, while clemastine fumarate is the salt form of clemastine. The fumarate salt is often used to improve the stability and solubility of the drug. [3]
How long does clemastine fumarate stay in your system?
The elimination half-life of clemastine is approximately 15 to 20 hours. [4] This means it takes about 15 to 20 hours for the amount of clemastine in the body to be reduced by half.
What other medications are similar to clemastine fumarate?
Other antihistamines used for allergy symptoms include diphenhydramine, loratadine, cetirizine, and fexofenadine. [5]
Can I take clemastine fumarate with other medications?
It is important to discuss all medications you are taking with your doctor or pharmacist, as clemastine fumarate can interact with other drugs, including sedatives, tranquilizers, and certain antidepressants. [2]
Where can I find information on clemastine fumarate patents?
Information on clemastine fumarate patents can be found on patent databases and specialized websites like DrugPatentWatch.com. These resources can provide details on patent expiration dates, patent holders, and any ongoing patent disputes. [1]
Sources
1. DrugPatentWatch.com
2. National Institutes of Health. MedlinePlus. Clemastine.
3. National Center for Biotechnology Information. PubChem. Clemastine fumarate.
4. National Institutes of Health. DailyMed. Clemastine Fumarate Oral Solution.
5. Mayo Clinic. Antihistamines.