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How can people manage pain without relying on ibuprofen? Many turn to acetaminophen, naproxen, or aspirin. Acetaminophen eases mild pain and fever but does not reduce inflammation, while naproxen and aspirin offer similar anti-inflammatory effects and last longer in the body. What happens if someone cannot take any NSAID? Doctors may recommend topical analgesics, physical therapy, or non-drug options such as heat, ice, rest, or gentle exercise. These approaches avoid stomach and kidney risks that come with oral NSAIDs. Can prescription drugs replace over-the-counter ibuprofen? In some cases physicians prescribe COX-2 inhibitors like celecoxib, which cause fewer gastrointestinal side effects, or stronger opioids for short-term severe pain. When does the patent on common ibuprofen brands expire? Most branded versions of ibuprofen have long been off patent, allowing many generic manufacturers to produce lower-cost versions. Generic competition keeps prices low and increases product availability. Which companies make the main ibuprofen alternatives? Acetaminophen is produced by Johnson & Johnson under Tylenol and by many generic firms. Naproxen is sold as Aleve by Bayer and as generics. Celecoxib is marketed by Pfizer as Celebrex and by several generic makers.
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