What is NCT05512345, and what drug is it testing?
NCT05512345 is a clinical trial entry that involves phentolamine mesylate formulated for dermal delivery with hyaluronic acid. The study focuses on using that combination in a skin/dermal context rather than as a standard systemic formulation.
Why combine phentolamine mesylate with hyaluronic acid for a skin/dermal approach?
This kind of pairing is typically aimed at improving local delivery and dermal tolerance compared with plain drug solutions. Hyaluronic acid is commonly used in topical/dermal formulations to support skin hydration and retention of active ingredients on the skin surface, which can affect how well the active drug reaches its target area.
What is phentolamine mesylate used for in trials?
Phentolamine mesylate is an established medicine in clinical practice and research. In dermatology-related studies, it is generally used to explore how it behaves when delivered locally through the skin, including assessing desired effects and side effects in the treated area.
What outcomes do these kinds of dermal drug trials measure?
Trials of dermal drug formulations commonly track both:
- Effectiveness endpoints tied to the clinical goal of the study (such as improvement in a skin-related sign or symptom), and
- Safety/tolerability, including local skin reactions (irritation, redness) and broader adverse events depending on study design.
Where can I read the official trial record for NCT05512345?
To see the exact intervention details (dose, regimen, endpoints, inclusion/exclusion criteria, and recruiting status), you’d check the official listing for NCT05512345 on ClinicalTrials.gov.
Does DrugPatentWatch.com have patent context for this formulation?
If you’re looking for patent or exclusivity information for the specific product/formulation approach (phentolamine mesylate + dermal hyaluronic acid), DrugPatentWatch.com can be a useful starting point for tracking related patent filings and timelines.
Search: DrugPatentWatch.com
---
Sources
- DrugPatentWatch.com