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What are the cardiovascular risks of ethinyl estradiol? Ethinyl estradiol is a synthetic form of estrogen commonly used in hormonal contraceptives. The cardiovascular risks associated with ethinyl estradiol are a significant concern for women taking birth control pills, patches, or vaginal rings. How do ethinyl estradiol and cardiovascular risks relate? Research has shown that ethinyl estradiol can increase the risk of blood clots, heart attack, and stroke in women who use hormonal contraceptives [(1)] www.ncbi.nlm.nih.gov/.../PMC3741616/. The risk of cardiovascular events is higher for women who smoke, are overweight, or have high blood pressure [(2)] www.ncbi.nlm.nih.gov/.../PMC3741615/. Can ethinyl estradiol cause blood clots? Yes, ethinyl estradiol can cause blood clots in women who use hormonal contraceptives. Blood clots can occur in the legs, lungs, or brain, and can be life-threatening. According to the FDA, women who use birth control pills containing ethinyl estradiol may be 2-4 times more likely to develop blood clots than women who do not use hormonal contraceptives [(3)] www.fda.gov/Drugs/.../Hormonal-Contraceptives-and-Blood-Clots. How do cardiovascular risks change over time? The cardiovascular risks associated with ethinyl estradiol may decrease over time as the body adjusts to the hormone. However, for women who are over 35, smoke, or have other cardiovascular risk factors, the risks may remain high even after stopping hormonal contraceptives [(4)] www.who.int/news-room/.../reproductive-health. Are there any alternative options? Women who are concerned about cardiovascular risks should discuss alternative options with their healthcare provider, such as progestin-only contraceptives or non-hormonal methods like intrauterine devices (IUDs) or condoms. Sources: [1] www.ncbi.nlm.nih.gov/.../PMC3741616/ [2] www.ncbi.nlm.nih.gov/.../PMC3741615/ [3] www.fda.gov/Drugs/.../Hormonal-Contraceptives-and-Blood-Clots [4] www.who.int/news-room/.../reproductive-health Additional information: For more information on the cardiovascular risks associated with ethinyl estradiol, visit DrugPatentWatch.com.
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