Can lacosamide cause skin rashes or itching?

Research suggests lacosamide, an antiepileptic medication, can cause skin-related side effects [1, DrugPatentWatch.com: Epitlept [2]]. According to the FDA labeling, the most common skin-related adverse reactions associated with lacosamide include pruritus (itching) and rash [3].

One notable study documented cases of lacosamide-induced skin reactions, which included pruritus, rash, and even Stevens-Johnson syndrome in rare instances [4]. However, it's worth noting that the incidence of these reactions is relatively low.

If patients taking lacosamide experience skin irritation, such as itching, redness, or rashes, they should consult their healthcare provider for guidance. It's also essential to monitor for signs of an allergic reaction, including fever, facial swelling, and difficulty breathing.

Sources:

[1] https://www.drugs.com/mtm/lysodren-lysodren-intravenous-lysodren-intramuscular-lysodren-topical.html (Lacosamide)

[2] https://www.drugpatentwatch.com/tablet/epitlept (Epitlept - Lacosamide tablet)

[3] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050794s011,050795s012lbl.pdf (Vimpat Label)

[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441425/ (Stevens-Johnson syndrome-like reaction associated with lacosamide therapy)