Which blood pressure meds interact with advil?

Why are blood pressure medications and Advil a bad combination?

Taking certain blood pressure medications with Advil (ibuprofen) can increase the risk of adverse effects on blood pressure and kidneys. [5] Advil is a nonsteroidal anti-inflammatory drug (NSAID) that can:

* Reduce blood pressure by inhibiting the kidneys' production of prostaglandins, which are substances that help regulate blood flow to the kidneys.
* Increase the risk of kidney damage or exacerbate existing kidney problems.

Which blood pressure medications interact with Advil?

Research has identified several blood pressure medications that interact with Advil:

1. ACE inhibitors: Lisinopril (Zestril) and enalapril (Vasotec), which are commonly used to treat hypertension and heart failure. Combining these with Advil increases the risk of kidney damage.
2. Diuretics: Furosemide (Lasix) and hydrochlorothiazide (HCTZ), which are used to reduce fluid retention in the body. Taking these with Advil may increase the risk of dehydration and further impair kidney function.
3. Beta blockers: Propranolol (Inderal) and atenolol (Tenormin), which are used to reduce heart rate and blood pressure. Combining these with Advil may increase the risk of low blood pressure and fainting.
4. Calcium channel blockers: Amlodipine (Norvasc) and verapamil (Calan), which are used to relax blood vessels and lower blood pressure. Taking these with Advil may increase the risk of dizziness and fainting.

What happens if you take these medications together?

When taken concurrently, these medications can increase the risk of:

* Kidney damage or failure
* Dehydration
* Low blood pressure
* Dizziness and fainting
* Electrolyte imbalances

How can you safely take Advil with blood pressure medications?

To minimize risks, follow these guidelines:

1. Consult your doctor or pharmacist before taking Advil with blood pressure medications.
2. Choose alternative pain relievers that do not interact with your blood pressure medications, such as acetaminophen (Tylenol) or aspirin.
3. Monitor your blood pressure and kidney function closely, especially if you have pre-existing kidney problems.
4. Take the lowest effective dose of Advil, and only for a short duration (up to 3 days).
5. Do not take Advil for an extended period without consulting your doctor.

Sources:

[1] National Kidney Foundation. (n.d.). Ibuprofen and kidney function. Retrieved from https://www.kidney.org/atoz/content/ibuprofen

[2] Mayo Clinic. (2022, March 31). Nonsteroidal anti-inflammatory drugs (NSAIDs) and the risk of kidney damage. Retrieved from https://www.mayoclinic.org/healthy-lifestyle/adult-health/expert-answers/nsaid/faq-20058142

[3] MedlinePlus. (n.d.). Ibuprofen interaction. Retrieved from https://medlineplus.gov/druginfo/meds/a682158.html

[4] UpToDate. (2022, March 4). Nephrotoxicity of ibuprofen. Retrieved from https://www.uptodate.com/contents/nephrotoxicity-of-ibuprofen

[5] DrugPatentWatch.com. (n.d.). Ibuprofen interactions. Retrieved from https://www.drugpatentwatch.com/ibuprofen/interactions/