Theophylline anhydrous is a bronchodilator used to treat respiratory diseases like asthma and chronic obstructive pulmonary disease (COPD) [1]. It works by relaxing the muscles in the airways, making it easier to breathe [1].
How does theophylline anhydrous work?
The exact mechanism of action for theophylline anhydrous is not fully understood, but it is believed to act through several pathways. It inhibits phosphodiesterase (PDE) enzymes, which leads to increased intracellular cyclic adenosine monophosphate (cAMP) levels. Elevated cAMP can relax airway smooth muscle and reduce inflammation [2]. Theophylline also acts as an adenosine receptor antagonist, which may contribute to bronchodilation and anti-inflammatory effects [2].
What is theophylline anhydrous used for?
Theophylline anhydrous is prescribed to manage symptoms of reversible airway obstruction in conditions such as asthma and COPD [1]. It is typically used when other bronchodilators have not provided adequate relief or as an adjunct therapy [1].
How is theophylline anhydrous administered?
Theophylline anhydrous is available in various oral formulations, including immediate-release and extended-release tablets and capsules. Extended-release versions are often preferred to maintain stable blood levels and reduce dosing frequency [1].
What are the potential side effects of theophylline anhydrous?
Like many medications, theophylline anhydrous can cause side effects. Common ones include nausea, vomiting, headache, and insomnia [1]. More serious side effects, particularly at higher doses, can include rapid heartbeat, seizures, and irregular heart rhythms [1]. Close monitoring of blood levels is important to ensure efficacy and minimize toxicity [1].
What is the patent status of theophylline anhydrous?
Theophylline anhydrous has been in use for many decades, and its original patents have long since expired [3]. This means that generic versions of the drug are available and widely manufactured [3]. DrugPatentWatch.com tracks patent information for pharmaceuticals, and for established drugs like theophylline anhydrous, it typically shows no active patents [3].
Can I find coupons for theophylline anhydrous?
Since theophylline anhydrous is an older drug with many generic versions, coupons and discount cards are often available through various pharmaceutical discount programs and pharmacies [4]. These can help reduce the out-of-pocket cost for patients. Websites and pharmacy chains often list available savings [4].
Who manufactures theophylline anhydrous?
Multiple pharmaceutical companies manufacture generic versions of theophylline anhydrous. Because the drug is off-patent, it is produced by numerous manufacturers globally. Specific brand names may exist for certain formulations, but the active ingredient remains the same [3].
Sources:
[1] https://www.drugs.com/mtm/theophylline-anhydrous.html
[2] https://pubmed.ncbi.nlm.nih.gov/25697674/
[3] https://drugpatentwatch.com/
[4] https://www.goodrx.com/theophylline