Standard Ozempic Dosing Schedule
Ozempic (semaglutide) is typically injected once weekly. Patients administer it subcutaneously, usually on the same day each week, with or without food. The starting dose is 0.25 mg weekly for 4 weeks, then 0.5 mg weekly. It can increase to 1 mg or 2 mg weekly based on response and tolerance.[1][2]
How to Time Injections
Choose a consistent day (e.g., every Monday). If delayed, inject as soon as possible within 5 days; otherwise, skip and resume the next scheduled day. Do not double doses. Rotate sites like abdomen, thigh, or upper arm.[1][2]
Dose Escalation Timeline
| Week | Typical Dose |
|------|--------------|
| 1-4 | 0.25 mg |
| 5+ | 0.5 mg |
| After 4 weeks at 0.5 mg | 1 mg (or up to 2 mg if needed) |
Escalation aims to minimize nausea. Maximum is 2 mg weekly.[1]
What If a Dose Is Missed?
Inject within 5 days. If more than 5 days late, skip it and take the next dose on schedule. Missing doses may reduce blood sugar control.[1][2]
Storage and Administration Tips
Store pens in the fridge (36-46°F). Unopened pens last until expiration; opened ones up to 56 days at room temperature (up to 86°F). Use new needle each time. NovoFine needles are recommended.[1]
Who Decides the Schedule?
Dosing follows FDA-approved labeling for type 2 diabetes or weight management. Doctors adjust based on A1C goals, side effects, or kidney function. Not for type 1 diabetes.[1][2]
[1]: Ozempic Prescribing Information (Novo Nordisk)
[2]: FDA Label for Ozempic