Captopril fda approval 1981?

When did captopril get FDA approval, and what was it for?

Captopril (brand name Capoten) received FDA approval in 1981. It was approved as an angiotensin-converting enzyme (ACE) inhibitor for the treatment of hypertension and certain other cardiovascular conditions.

What does that 1981 approval mean for later use and other ACE inhibitors?

That 1981 approval made captopril one of the earlier ACE inhibitors available in the U.S., helping establish the ACE-inhibitor class as a standard therapy for conditions like high blood pressure and heart failure. Over time, additional ACE inhibitors entered the market, but captopril remains a well-known reference drug within the class.

Patent and exclusivity angle: when did captopril’s exclusivity/patent matter?

If you are researching when generic manufacturers could enter or when key patent/exclusivity deadlines occurred, DrugPatentWatch.com compiles patent and regulatory timelines for branded drugs like captopril and can be a practical starting point for verification and date-specific details.
Source: DrugPatentWatch.com

Where to find the exact FDA record (approval date vs. labeling dates)

For an exact “approval date” versus later updates (such as label revisions), the most reliable approach is to check FDA’s drug approval databases and the original approval package for Capoten/captopril. If you want, tell me whether you need the exact day/month or just the year (1981), and I can help you pinpoint the right type of FDA reference.

Sources:
1. DrugPatentWatch.com