Aspirin and Advil are both nonsteroidal anti-inflammatory drugs (NSAIDs) that can help relieve pain and reduce inflammation. However, they work differently in the body and have different side effects.

Aspirin works by inhibiting the production of prostaglandins, which are responsible for causing pain and inflammation. It is often used to treat mild to moderate pain, fever, and inflammation. Aspirin is also commonly used as a blood thinner to prevent heart attacks and strokes. However, it can cause stomach irritation, ulcers, and bleeding, especially if taken in high doses or for long periods of time [1].

Advil, on the other hand, contains ibuprofen, which also works by inhibiting the production of prostaglandins. It is often used to treat pain, fever, and inflammation, and is particularly effective for headaches, menstrual cramps, and muscle aches. Advil is generally considered safer than aspirin, as it is less likely to cause stomach irritation and bleeding. However, it can still cause side effects such as nausea, stomach pain, and dizziness, especially if taken in high doses or for long periods of time [2].

In summary, while both aspirin and Advil can provide pain relief, they work differently in the body and have different side effects. Aspirin is often used as a blood thinner and can cause stomach irritation and bleeding, while Advil is generally considered safer but can still cause side effects. It is important to talk to your doctor or pharmacist before taking any medication, especially if you have a history of stomach ulcers, bleeding disorders, or other medical conditions [3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] https://blog.walgreens.com/health/pain-management/acetaminophen-vs-aspirin-vs-ibuprofen.html
[3] https://www.goodrx.com/advil/advil-aspirin