How do i reconstitute pregnyl?

How do I reconstitute Pregnyl at home?

Mix the supplied solvent with the powder in the vial. Draw the solvent into a syringe and inject it slowly along the inner wall of the vial so the powder dissolves without foaming. Gently swirl or roll the vial until the solution is clear; do not shake it. The resulting liquid should be used immediately or stored in the refrigerator and used within the time stated on the label.

What volume of solvent should I use?

The package insert specifies the amount of solvent supplied for each strength. For a 5,000 IU vial the common volume is 1 mL bacteriostatic water, yielding a 5,000 IU/mL solution. For a 10,000 IU vial the volume is usually 2 mL. Confirm the exact volume on your specific kit before mixing.

Can I use plain sterile water instead of bacteriostatic water?

Plain sterile water works for single-use doses that will be injected right away, but bacteriostatic water is preferred when any portion will be stored and reused, because the added preservative slows bacterial growth.

How long does reconstituted Pregnyl stay stable?

When mixed with bacteriostatic water and kept refrigerated at 2–8 °C, the solution remains stable for up to 30 days according to most prescribing information. Discard any unused solution after that period or if it becomes cloudy or discolored.

What happens if the powder does not dissolve completely?

If particles remain after gentle swirling, continue rolling the vial between your palms for another minute. Persistent cloudiness or undissolved material means the solution should not be injected; contact the pharmacy or prescriber for a replacement.

Why do some patients split doses after reconstituting?

Splitting allows smaller, more frequent injections that some protocols use to maintain steadier hormone levels. After reconstitution, draw the desired portion into an insulin syringe and store the remainder in the original vial under refrigeration.

When should I discard an opened vial?

Throw the vial away if more than 30 days have passed since reconstitution, if the solution looks cloudy, contains particles, or if sterility may have been compromised by repeated needle punctures.

Who makes Pregnyl and where can I check patents?

Pregnyl is manufactured by Merck Sharp & Dohme and marketed in many countries under that brand. Patent and exclusivity data are tracked on DrugPatentWatch.com.