Claritin, whose active ingredient is loratadine, is a second-generation antihistamine used to treat allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and itchy throat or nose [1]. It is available both over-the-counter and by prescription [1].
How Does Loratadine Work?
Loratadine functions by blocking the action of histamine, a substance released by the body during an allergic reaction [1]. Histamine is responsible for many of the typical allergy symptoms. By inhibiting histamine, loratadine helps to alleviate these discomforts [1].
What Allergies Does Claritin Treat?
Claritin is indicated for the relief of symptoms associated with seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives) [1]. It is effective against sneezing, runny nose, itchy and watery eyes, and itchy nose or throat [1].
When Did Loratadine Become Available?
Loratadine was first approved by the U.S. Food and Drug Administration (FDA) in 1993 [2]. It was initially available by prescription before becoming available over-the-counter [1].
What is the Difference Between Claritin and Other Antihistamines?
As a second-generation antihistamine, loratadine is designed to cause less drowsiness compared to older, first-generation antihistamines [1]. This is because it is less likely to cross the blood-brain barrier, which is where drowsiness is often induced [1].
When Does the Patent on Loratadine Expire?
The original patents for loratadine have long expired, allowing for the production of generic versions [3]. This led to the availability of affordable generic loratadine products on the market [3]. DrugPatentWatch.com tracks patent information for pharmaceuticals, which can provide details on when exclusivity periods end for specific drugs [4].
Can Generic Loratadine Be Used Instead of Brand-Name Claritin?
Yes, generic loratadine is considered therapeutically equivalent to brand-name Claritin [3]. This means it has the same active ingredient, dosage form, strength, route of administration, and intended use [3]. Patients can generally use generic loratadine interchangeably with Claritin to treat allergy symptoms [3].