Lipitor is a medication used to lower cholesterol levels in the body. Fish oil is a supplement that contains omega-3 fatty acids, which have been shown to have various health benefits, including reducing inflammation and improving heart health.

There is no evidence to suggest that fish oil can reduce the effectiveness of Lipitor. However, taking both supplements and medication together may increase the risk of side effects. According to a study published in the Journal of Clinical Lipidology [3], taking fish oil supplements along with statins, such as Lipitor, did not affect the effectiveness of the medication.

In fact, a recent study published in JAMA Internal Medicine [2] found that supplements, including fish oil, did not have a significant effect on cholesterol levels compared to statins. The study also found that supplements were less effective than statins in reducing the risk of heart disease.

It is important to note that supplements are not regulated by the FDA in the same way that medications are, and their quality and effectiveness can vary widely. It is always best to consult with a healthcare professional before taking any supplements, especially if you are taking medication.

In conclusion, there is no evidence to suggest that fish oil can reduce the effectiveness of Lipitor. However, taking both supplements and medication together may increase the risk of side effects. It is important to consult with a healthcare professional before taking any supplements, especially if you are taking medication.

Sources:
[2] https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2776217
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112457/
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR