See the DrugPatentWatch profile for valtoco
What dose of Valtoco (diazepam nasal spray) is used for children?
Valtoco is dosed based on the child’s age and the number of doses needed for the seizure event. The dosing schedule in the U.S. is:
- Age 6 to under 12 years: 10 mg nasal spray (one dose).
If needed, a second dose can be given 4 hours after the first.
- Age 12 years and older: 20 mg nasal spray (one dose).
If needed, a second dose can be given 4 hours after the first.
These doses are intended for the treatment of a known, existing seizure cluster (also referred to as prolonged seizures or acute repetitive seizures) when it’s been prescribed by a clinician.
Can a child get a second dose? How long to wait?
Yes. The second dose—if prescribed and needed—is given 4 hours after the first dose. The medication labeling also emphasizes that dosing should follow the specific prescription instructions for the patient’s seizure plan.
What strength should you use: 10 mg vs 20 mg?
For children aged 6 to under 12 years, the prescribed dose is 10 mg total, which corresponds to the 10 mg Valtoco nasal spray strength.
For children aged 12 years and older, the prescribed dose is 20 mg total, which corresponds to the 20 mg strength.
What if the child is under 6?
The standard pediatric dosing schedule described above covers ages 6 and older. If the child is under 6, the correct dose should be determined by the prescribing clinician using the patient’s seizure plan and any labeling guidance for that age group.
Important safety check: when should you not rely on age alone?
Age-based dosing is only one part of the seizure action plan. A clinician may adjust instructions for:
- the child’s seizure pattern and caregiver plan,
- the timing of when to give Valtoco,
- and whether a second dose is allowed.
If you’re unsure which Valtoco strength matches the prescription or when to give the second dose, check the exact instructions on the child’s prescription label or the seizure action plan.
Sources