Lipitor is a widely used medication that is primarily prescribed to lower cholesterol levels in patients with high cholesterol. The active ingredient in Lipitor is atorvastatin, which works by inhibiting the enzyme HMG-CoA reductase, which is responsible for the production of cholesterol in the liver [1]. As with any medication, there are potential side effects that patients should be aware of, including the possibility of liver function test abnormalities.

According to a recent study, there is evidence to suggest that statins, including Lipitor, may cause mild elevations in liver enzymes in some patients [2]. However, these elevations are typically not clinically significant and do not require discontinuation of the medication. The study also found that patients with pre-existing liver disease may be at a higher risk of developing liver enzyme abnormalities while taking statins.

While liver function test abnormalities are a potential side effect of Lipitor, it is important to note that they are relatively rare. According to Harvard Health Publishing, only about 1% of patients taking statins experience clinically significant elevations in liver enzymes [3]. However, patients taking Lipitor should still have their liver function tested periodically to monitor for any potential abnormalities.

In conclusion, Lipitor is a commonly prescribed medication for the treatment of high cholesterol. While it is possible for the medication to cause mild elevations in liver enzymes, this side effect is relatively rare and typically not clinically significant. Patients taking Lipitor should still have their liver function tested periodically to monitor for any potential abnormalities, particularly if they have pre-existing liver disease.

Sources:
[1] DrugPatentWatch. Lipitor. https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] NCBI. Statins and liver function tests: A systematic review and meta-analysis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526761/
[3] Harvard Health Publishing. Ask the doctor: Statins and liver tests. https://www.health.harvard.edu/diseases-and-conditions/ask-the-doctor-statins-and-liver-tests