Bezlotoxumab price?

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Bezlotoxumab price?

Accepted Answer

Bezlotoxumab (Xulane) – Typical Cost in the United States

Item	Information
Drug	Bezlotoxumab (monoclonal antibody for prevention of recurrent Clostridioides difficile infection)
Dosing	One intravenous infusion (usually 10 mg/kg, max 500 mg) given once
List Price	Roughly $13 000–$14 000 per infusion on the manufacturer’s (Merck) pricing sheet.
Medicare/Commercial Negotiated Rates	CMS (Medicare) and many commercial plans often negotiate a lower price—typically in the $4 000–$7 000 range per dose, depending on the payer contract.
Variability	Prices can vary significantly by:
– State or insurer contracts
– Pharmacy benefit manager (PBM) agreements
– Patient assistance or manufacturer coupons
– International pricing (often lower in many European, Asian, or Middle‑East markets)

Key points to remember

Single‑dose therapy – you pay once for the entire course.
Insurance coverage – Most insurance plans cover bezlotoxumab for patients who meet the FDA labeling criteria (high‑risk for recurrence). Always confirm pre‑authorization requirements with your insurer.
Patient assistance – Merck offers a program for eligible patients who cannot afford the drug. You can check the manufacturer’s website or speak with a pharmacist for eligibility.
Alternative options – If cost is a barrier, discuss other strategies (e.g., fidaxomicin, vancomycin taper, fecal microbiota transplantation) with your clinician to weigh benefits versus expense.

Bottom line
The publicly listed price is around $13 k–$14 k per infusion, but the amount you actually pay (after insurance or assistance) is usually much lower—often in the $4 k–$7 k ballpark. If you’re looking at a specific plan or country, it’s a good idea to request the exact cost from your pharmacy or insurer, as negotiated rates can differ.

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Bezlotoxumab price?