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How long can someone safely take aspirin daily? Daily low-dose aspirin is prescribed for heart protection and can be taken for years when a doctor monitors for stomach irritation and bleeding risk. What stomach problems occur with long-term aspirin? Aspirin blocks protective prostaglandins in the stomach lining, so regular use raises the chance of gastritis, ulcers, and gastrointestinal bleeding. Can aspirin damage the kidneys over time? Chronic aspirin use may reduce blood flow to the kidneys and, in people with existing kidney disease or dehydration, can worsen kidney function. Does aspirin increase bleeding risk in older adults? After age 60, the risk of major bleeding rises sharply, which is why many guidelines now limit aspirin for primary prevention in this group. How does aspirin interact with other common medicines? Combining aspirin with anticoagulants, NSAIDs, or certain blood-pressure drugs multiplies bleeding risk and can blunt the effect of some blood-pressure medicines. When should someone stop or switch aspirin therapy? If new stomach pain, black stools, or easy bruising appear, or if a new drug interaction is identified, a doctor may lower the dose, add a stomach-protective agent, or discontinue aspirin. What alternatives exist for people who cannot tolerate aspirin? Clopidogrel, low-dose rivaroxaban, or lifestyle measures such as blood-pressure control and statin therapy are options when aspirin causes side effects.
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