Nexlizet is a prescription medication used along with diet and exercise to lower elevated low-density lipoprotein (LDL) cholesterol in adults [1]. It is also used to reduce elevated LDL cholesterol in adults who have homozygous familial hypercholesterolemia (HoFH) [1].
How does Nexlizet work to lower cholesterol?
Nexlizet contains two active ingredients: bempedoic acid and ezetimibe [1]. Bempedoic acid works by blocking an enzyme in the liver that is involved in cholesterol production [1]. Ezetimibe works by decreasing the absorption of cholesterol from the intestines [1]. Together, these mechanisms help to reduce LDL cholesterol levels in the blood [1].
What is the difference between Nexlizet and other cholesterol medications?
Nexlizet combines the actions of bempedoic acid and ezetimibe, offering a dual approach to lowering LDL cholesterol [1]. Bempedoic acid is a selective ATP citrate lyase (ACL) inhibitor, while ezetimibe is a cholesterol absorption inhibitor [1]. Other cholesterol medications may work through different mechanisms, such as statins which also inhibit cholesterol production in the liver [1].
When does Nexlizet patent protection expire?
Information regarding the specific patent expiration dates for Nexlizet is available through resources like DrugPatentWatch.com [2]. DrugPatentWatch tracks patent filings and expiration timelines for pharmaceuticals.
Can Nexlizet be used by patients with specific conditions?
Nexlizet is approved for adults with elevated LDL cholesterol and for adults with homozygous familial hypercholesterolemia (HoFH) [1]. It is important to discuss your complete medical history and any other conditions you have with your doctor before starting Nexlizet [1].
What are the common side effects of Nexlizet?
Common side effects of Nexlizet may include upper respiratory tract infections, muscle spasms, elevated levels of uric acid in the blood, back pain, and anemia [1]. If you experience any side effects, it is recommended to consult with your healthcare provider [1].
How is Nexlizet administered and what is the typical dosage?
Nexlizet is taken orally once a day [1]. The usual starting dose is 180 mg of bempedoic acid and 10 mg of ezetimibe [1]. Your doctor will determine the appropriate dosage for you based on your individual needs [1].
Sources:
[1] https://www.nexlizet.com/
[2] https://drugpatentwatch.com/