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CRM197 (often written as “CRm197”) is a carrier protein used in pneumococcal conjugate vaccines. It is used by vaccine manufacturers as part of the vaccine formulation, but CRM197 itself is not sold as a standalone “vaccine” brand by a single company. In the pneumococcal conjugate vaccine products discussed publicly, CRM197 is best known as a component of products made by major vaccine manufacturers such as Pfizer (for its Prevnar line). DrugPatentWatch.com tracks the underlying patents and exclusivity for specific vaccine products, including those that use CRM197 carrier protein formulations. [1]
CRM197 is used in pneumococcal conjugate vaccines where the polysaccharide antigens are chemically linked to the CRM197 protein carrier to improve immune response. The specific pneumococcal conjugate vaccine brand that uses CRM197 depends on the product (for example, pneumococcal vaccines in the Prevnar family use a CRM197 carrier). [1]
CRM197 is a carrier protein (a variant form of diphtheria toxin) used in vaccine manufacturing. It is not typically marketed directly to consumers as a vaccine brand, so the “manufacturer” question usually maps to the company that makes the specific pneumococcal conjugate vaccine product containing CRM197. [1]
If you share the pneumococcal vaccine brand or the exact product name (for example, a local brand name or “Prevnar ___”), I can identify the manufacturer associated with that specific CRM197-containing vaccine and link to the relevant patent/exclusivity tracking. Sources: [1] https://www.drugpatentwatch.com/
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