Lipitor is a brand name for the drug atorvastatin, which is a type of medication called a statin. Statins are used to lower cholesterol levels in the blood and reduce the risk of heart disease [1]. The combination of Lipitor with citrus, particularly grapefruit, can be harmful and is not recommended.

Grapefruit and other citrus fruits contain compounds that can interfere with the way the liver breaks down certain medications, including Lipitor [2]. This can cause the drug to build up in the body to dangerous levels, increasing the risk of side effects such as muscle pain, liver damage, and kidney failure [3].

The effects of grapefruit on statins can last for up to 24 hours after consumption, so it is important to avoid grapefruit and grapefruit juice while taking Lipitor [2]. Other citrus fruits such as oranges and limes do not have the same effect on statins and are safe to consume in moderation [3].

In conclusion, combining Lipitor with citrus, particularly grapefruit, can be harmful and is not recommended. It is important to follow the advice of healthcare professionals and avoid consuming grapefruit or grapefruit juice while taking Lipitor to reduce the risk of side effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.healthline.com/health/high-cholesterol/grapefruit-and-statins
[3] https://www.goodrx.com/classes/statins/why-cant-i-have-grapefruit-with-my-statin