Risdiplam spiro patent?

Do you mean a patent about risdiplam that uses a spiro (spirocyclic) core, or are you asking for the patent coverage around risdiplam in general (composition, use for SMA, synthesis)? I can help, but I want to be sure what you’re after.

What I can tell at a high level
- Risdiplam (also known as RG7916 or RO7034067) is a Roche/genentech SMA drug that acts as a SMN2 splicing modifier.
- There are multiple patent families from Hoffmann-La Roche and related entities around risdiplam, covering:
- the chemical composition itself (composition-of-matter)
- methods of use for treating spinal muscular atrophy
- synthesis and manufacturing processes
- I don’t have a verified “spiro patent” specifically tied to risdiplam. If a particular patent claims a spirocyclic scaffold in risdiplam or a related class, I’d need to look at that exact document to confirm.

How to find and verify patents yourself (recommended)
- Google Patents: search for “risdiplam OR RG7916 OR RO7034067” and filter by assignee (Roche) and by status. Then search within the results for mentions of “spiro” if you’re specifically looking for a spirocore.
- Espacenet and WIPO PATENTSCOPE: use the same search terms, and you can drill down by family to see all national filings.
- Useful search strings:
- risdiplam
- RG7916
- RO7034067
- “spiro” AND risdiplam (to check for any spiro motifs)
- “splicing modifier” AND SMA AND risdiplam
- If you have a patent number or a country of interest (e.g., US, EU, China), I can summarize the claims and status for that document.

If you want, tell me:
- Whether you want a general landscape summary or you have a specific patent/Country number to review
- Whether you’re specifically after spiro-containing patents or just risdiplam-related IP overall

Note: I can guide you and summarize documents, but for legal decisions or freedom-to-operate analyses, you should consult a patent attorney.