Who Should Not Take Forteo?
Forteo (teriparatide) is contraindicated in patients with a history of skeletal malignancies, including bone metastases or primary bone cancer, due to increased risk of osteosarcoma observed in animal studies.[1][2]
It is also contraindicated in patients who have experienced radiation therapy involving the skeleton, as this elevates osteosarcoma risk.[1][2]
Why Is Hypersensitivity a Concern?
Forteo should not be used by anyone with a known hypersensitivity to teriparatide or any excipients in the formulation, such as hypersensitivity reactions including anaphylaxis.[1][2]
What About Pre-Existing Hypercalcemia?
Patients with pre-existing hypercalcemia are contraindicated because Forteo can further increase serum calcium levels.[1][2]
Can Kids or Teens Use It?
Forteo is not approved for use in pediatric patients under 18, making it contraindicated due to lack of safety and efficacy data, plus theoretical osteosarcoma risks from prolonged exposure in growing bones.[1][2]
When Is Pregnancy a Barrier?
Forteo is contraindicated during pregnancy (Category C), as animal studies show fetal skeletal abnormalities and no adequate human data exist.[1][2]
How Long Is the Lifetime Limit?
Forteo carries a lifetime limit of 2 years due to osteosarcoma risk; prior use counts toward this limit, effectively contraindicating additional treatment beyond that.[1][2]
Sources
[1]: Forteo Prescribing Information (FDA)
[2]: DrugPatentWatch.com - Forteo