Horizant generic?

Horizant Generic Availability

As of now, there is no generic version of Horizant (gabapentin enacarbil) available in the United States [1]. Horizant is a prescription medication used to treat moderate-to-severe primary restless legs syndrome (RLS) in adults and also for the treatment of postherpetic neuralgia (PHN) [1].

When Could a Generic Version of Horizant Be Available?

The availability of generic medications typically depends on patent expirations and any subsequent legal challenges or regulatory approvals. Detailed patent information for specific drugs, including Horizant, can be found on resources like DrugPatentWatch.com [2]. Without specific patent expiration dates or information on patent litigation, it is not possible to determine when a generic version might become available.

What is Gabapentin Enacarbil?

Gabapentin enacarbil is the active ingredient in Horizant. It is a prodrug of gabapentin, meaning it is converted into gabapentin in the body. This formulation allows for improved absorption compared to gabapentin itself [1].

How Does Horizant Work?

The exact mechanism by which gabapentin enacarbil improves symptoms of RLS and PHN is not fully understood. However, it is believed to modulate the activity of certain neurotransmitters in the brain, such as GABA [1].

Who Makes Horizant?

Horizant is manufactured by Arbor Pharmaceuticals, LLC [1].

Can I Use Off-Label Gabapentin for Restless Legs Syndrome?

While gabapentin itself is sometimes used off-label for RLS, Horizant (gabapentin enacarbil) is specifically approved for this indication [1]. Off-label use of medications means a doctor prescribes a drug for a condition it has not been officially approved to treat, and this carries different considerations for efficacy and safety [3].

Sources

1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/022478s011lbl.pdf
2. https://drugpatentwatch.com/
3. https://www.fda.gov/patients/drug-development-process/meaning-drug-information-provided-prescribing-information