According to the sources provided, the dosage of lacosamide should be adjusted based on individual patient response and tolerability. The optimal dosage of lacosamide varies depending on the specific condition being treated, such as partial-onset seizures in adults or pediatric patients.
The recommended starting dose for lacosamide is typically 50 mg twice daily, which can be increased by 100 mg per day every week until the desired therapeutic effect is achieved. The maximum recommended daily dose is 400 mg for adults and 12 mg/kg for pediatric patients.
It is important to note that the dosage adjustment should be done under the supervision of a healthcare professional, such as a neurologist or epileptologist. They will assess the patient's response to the medication and make appropriate adjustments based on factors such as seizure control and any potential side effects.
Regular monitoring of the patient's response to lacosamide is crucial to determine if any dosage adjustments are necessary. This may include evaluating the frequency and severity of seizures, as well as assessing any adverse effects that may occur.
In summary, the dosage of lacosamide should be adjusted on an individual basis, starting with a recommended initial dose and gradually increasing until the desired therapeutic effect is achieved. Regular monitoring by a healthcare professional is necessary to assess the patient's response and make any necessary dosage adjustments.
Sources:
[1] DrugPatentWatch. (n.d.). Lacosamide - Tradename: Lacosamide. Retrieved from https://www.drugpatentwatch.com/p/tradename/LACOSAMIDE
[2] Epilepsy Foundation. (n.d.). Lacosamide. Retrieved from https://www.epilepsy.com/tools-resources/seizure-medication-list/lacosamide
[3] Drugs.com. (n.d.). Lacosamide Dosage. Retrieved from https://www.drugs.com/dosage/lacosamide.html