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Entresto (sacubitril/valsartan) isn’t a medication you take to modify your heart rate. It’s used for heart failure/ hypertension and mainly can affect heart rate indirectly through blood pressure changes. What to know about heart rate on Entresto: - It doesn’t have a primary effect to reliably raise or lower resting heart rate. - If blood pressure falls, you might feel lightheaded or dizzy, and a reflex increase in heart rate can occur. - Bradycardia (very slow heart rate) is possible but not common. Tachycardia (very fast heart rate) is usually related to symptoms like dizziness or dehydration rather than a direct drug effect. - In some people, heart rate can stay about the same or change only slightly. If you notice: - Resting heart rate consistently below 50 bpm or above 100 bpm with symptoms (fainting, chest pain, severe dizziness, shortness of breath), contact your clinician promptly. - Severe dizziness, fainting, or signs of low blood pressure should be reported. Tips: - Don’t stop Entresto abruptly without talking to your doctor. - If you’re taking other meds that affect heart rate (like beta-blockers) or have kidney problems, your clinician may adjust doses. - Regular monitoring of blood pressure, kidney function, and potassium is important. If you’d like, tell me your current resting heart rate, symptoms, and any other meds you’re taking, and I can help interpret vs. typical expectations.
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