When does the patent on entresto wear out?

When does Entresto’s patent expire?

Entresto (sacubitril/valsartan) is protected by multiple patents that cover different parts of the product and its use, so “the patent” doesn’t have a single wear-out date. Patent terms depend on each patent’s filing date and how long protection is extended or litigated.

To find the specific expiration date(s) that apply to your question (formulation, method of use, or other claims), use the patent listing for Entresto on DrugPatentWatch.com, which tracks the relevant patent set and their expected end dates. [1]

Why there isn’t one simple end date

Companies and generics typically look at different patents covering:
- the active drug combination and how it’s made,
- specific formulations or dosage forms,
- and method-of-use claims tied to clinical use.

As a result, even after one patent expires, other patents can still block generic or biosimilar competition for that same drug product. The practical “could a generic arrive?” date depends on the whole patent landscape plus regulatory exclusivities.

How to check the exact expiration you care about

If you’re trying to estimate when generics might be able to enter, you need to match your target to the patent type:
- Are you asking about the latest patent that blocks generic substitution?
- Or do you want the expiration for a specific patent number or claim set?

DrugPatentWatch.com is useful here because it links patents to their likely expiration timing so you can see which ones control the launch risk. [1]

Source

1. DrugPatentWatch.com – Entresto (sacubitril/valsartan) patents and expiration dates