There is no publicly available information regarding the specific price of Nurtec ODT 75 mg in India. Pricing for medications can vary significantly based on market factors, import duties, and local distribution agreements.
What is Nurtec ODT?
Nurtec ODT, also known by its generic name rimegepant, is an oral medication used for the acute treatment of migraine with or without aura in adults [1]. It is also approved for the preventive treatment of episodic migraine in adults [2]. The drug works by inhibiting the activity of calcitonin gene-related peptide (CGRP), a molecule that plays a role in migraine pain [3].
When did Nurtec ODT receive FDA approval?
Nurtec ODT received its initial U.S. Food and Drug Administration (FDA) approval in December 2019 for the acute treatment of migraine [1]. It later received approval for the preventive treatment of episodic migraine in June 2021 [2].
Who manufactures Nurtec ODT?
Nurtec ODT is manufactured by Biohaven Pharmaceuticals, which was acquired by Pfizer in 2022 [4].
What is the difference between Nurtec ODT and other migraine treatments?
Nurtec ODT belongs to a class of drugs called gepants, which target CGRP [3]. Unlike older migraine medications such as triptans, which constrict blood vessels, gepants work by blocking the action of CGRP [5]. This mechanism may offer an alternative for patients who do not respond to or cannot tolerate triptans [5].
What are the potential side effects of Nurtec ODT?
Common side effects of Nurtec ODT include nausea and upper respiratory tract infections [1]. Less common side effects have also been reported. Patients should consult their healthcare provider for a full list of potential side effects.
What is the patent status for Nurtec ODT?
Information on the specific patent expiry dates for Nurtec ODT in various regions, including India, is not readily available. DrugPatentWatch.com is a resource that tracks patent information for pharmaceutical products [6]. Generally, patent protection for drugs can vary, and challenges to patents can influence market entry for generic versions.
Are there generic versions of Nurtec ODT available?
As of now, generic versions of Nurtec ODT are not available in the United States [7]. The availability of generics is typically tied to patent expiration and regulatory approvals.
What are the clinical trial results for Nurtec ODT?
Clinical trials have demonstrated Nurtec ODT's efficacy in both acute and preventive treatment of migraine. Studies showed that a significant percentage of patients treated with Nurtec ODT experienced pain freedom and freedom from their most bothersome migraine-associated symptom two hours after dosing for acute treatment [1]. For preventive treatment, trials indicated a reduction in monthly migraine days compared to placebo [2].
What is the dosage for Nurtec ODT?
For the acute treatment of migraine, the recommended dose of Nurtec ODT is 75 mg taken as needed [1]. For the preventive treatment of episodic migraine, the recommended dose is 75 mg taken every other day [2].
Sources:
[1] https://www.nurtec-otd.com/
[2] https://www.fda.gov/drugs/drug-approvals-and-databases/drug-approvals-and-labeling-2021
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409730/
[4] https://www.pfizer.com/news/press-release/press-release-detail/pfizer-completes-acquisition-biohaven-pharmaceuticals-holding
[5] https://www.mayoclinic.org/diseases-conditions/migraine-headache/in-depth/migraine-treatment/art-20047079
[6] https://drugpatentwatch.com/
[7] https://www.nurtec-otd.com/hcp/dosing-and-administration