Entresto (sacubitril/valsartan) 97/103 mg is a prescription medication used to treat heart failure with reduced ejection fraction. The price you see on the pharmacy shelf is the list price, which is the amount that most insurers negotiate with the manufacturer. In practice, the amount you actually pay can be much lower (or higher) depending on a few key factors:
| What you’re looking at | What it actually means |
|------------------------|------------------------|
| Manufacturer’s list price | The price the drug company publishes (often called the “MSRP” or “average wholesale price”). For Entresto 97/103 mg, the U.S. list price is roughly $2,200–$2,400 per month (≈ $1,800–$1,950 for a 30‑day supply). |
| Insurance coverage | Most commercial plans will cover Entresto, but the exact copay or coinsurance can vary. Some plans have a “step‑down” system: you might pay a modest copay until you reach a certain deductible, after which a larger percentage is taken. |
| Manufacturer assistance | Novartis (the manufacturer) offers a Patient Assistance Program (PAP) for eligible patients who can’t afford the copay. The program can cover the full cost of the medication for those who meet income and insurance criteria. |
| Pharmacy discount cards | Many pharmacy benefit managers (PBMs) and independent discount cards provide a 10‑30 % reduction on the list price, especially if you have no insurance or a high deductible. |
| Generic availability | As of now, there is no generic version of Entresto in the U.S., so the list price is the benchmark. |
How to figure out what you’ll actually pay
1. Check your insurance plan – Look at the formulary and see what copay or coinsurance applies to Entresto (usually a tiered cost sharing).
2. Call the pharmacy – Most pharmacies can run your insurance through their system and give you a real‑time estimate.
3. Ask about the PAP – If your insurance copay is high, call Novartis or visit their website to see if you qualify.
4. Compare discount cards – If you’re uninsured or underinsured, a pharmacy discount card (e.g., GoodRx, VSP) might save you 10‑30 % of the list price.
Quick ballpark
- Without insurance: ~$1,900–$2,200 for a 30‑day supply.
- With insurance (average): 20–40 % copay (≈ $380–$880) after deductible.
- With manufacturer assistance: 0 % copay for those who qualify.
Keep in mind that prices fluctuate, and the amount can differ by region, pharmacy, and insurer. If you’re having trouble paying, it’s worth talking to your prescriber’s office or a pharmacist; they often have additional resources or patient‑support programs that can help.