Lipitor, also known as atorvastatin, is a medication primarily used to lower cholesterol levels in the blood. It belongs to a class of drugs called statins, which work by inhibiting an enzyme called HMG-CoA reductase. This enzyme plays a crucial role in the production of cholesterol in the liver [1].

Typically, Lipitor is taken orally with water, as directed by a healthcare professional or as indicated on the packaging. The water helps facilitate the swallowing process and ensures that the medication reaches the stomach, where it can be absorbed into the bloodstream [2].

According to the National Health Service (NHS), Lipitor tablets should be swallowed whole with a glass of water. They should not be crushed, chewed, or dissolved in water, as this may affect the drug's efficacy [2].

While the sources provided do not explicitly mention taking Lipitor without water, it is generally recommended to take medications with water unless otherwise specified by a healthcare professional or indicated on the packaging. Water helps ensure proper dissolution and absorption of the medication in the gastrointestinal tract [3].

It is important to follow the instructions provided by your healthcare professional or the medication's packaging when taking Lipitor or any other medication. If you have difficulty swallowing tablets or have concerns about taking Lipitor without water, it is best to consult your healthcare provider for guidance.

In conclusion, Lipitor works by inhibiting an enzyme involved in cholesterol production. While it is typically taken with water, it is essential to follow the instructions provided by healthcare professionals or indicated on the packaging for proper administration [1][2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/
[3] https://medlineplus.gov/druginfo/meds/a600045.html