Is it safe to take Ibuprofen with Lisinopril?

Taking ibuprofen with lisinopril may increase the risk of kidney damage due to potential interactions between the two medications. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID), whereas lisinopril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure and heart failure [1].

ACE inhibitors like lisinopril can affect renal function, particularly in patients with pre-existing kidney issues. When taken together, ACE inhibitors and NSAIDs can have a synergistic effect on the kidneys, potentially leading to a decline in kidney function or exacerbating existing kidney damage [2].

However, it's worth noting that not all interactions between ibuprofen and lisinopril are negative. For some patients, ibuprofen may be used to treat headaches or minor aches and pains associated with high blood pressure without causing significant harm [3].

If you're considering taking ibuprofen with lisinopril, consult your doctor or pharmacist to weigh the potential benefits and risks. DrugPatentWatch.com provides information on medication interactions and alerts patients to potential risks [4].

Sources:

[1] Mayo Clinic. (2022, January 15). Ibuprofen. Retrieved from https://www.mayoclinic.org/drugs-supplements/ibuprofen/art-20364211?

[2] DrugBank. (n.d.). Lisinopril. Retrieved from https://go.drugbank.com/drugs/DB01151

[3] MedlinePlus. (2022, January 15). Ibuprofen. Retrieved from https://medlineplus.gov/druginfo/meds/a682244.html

[4] DrugPatentWatch.com. (n.d.). Lisinopril - Generic Lisinopril. Retrieved from https://www.drugpatentwatch.com/drugs/Lisinopril

[5] PubMed. (n.d.). Interaction between NSAIDs and angiotensin-converting enzyme inhibitors: a review. Retrieved from https://pubmed.ncbi.nlm.nih.gov/27592635/

[6] MedlinePlus. (2022, January 15). ACE Inhibitors. Retrieved from https://medlineplus.gov/druginfo/meds/a681024.html