Keppra is manufactured by UCB Pharma [1].
What is the generic name for Keppra?
The generic name for Keppra is levetiracetam [2].
What is levetiracetam used to treat?
Levetiracetam is an anti-epileptic drug used to treat partial-onset seizures, myoclonic seizures, and primary generalized tonic-clonic seizures in adults and children [2].
When does the Keppra patent expire?
Patent exclusivity for Keppra has expired in many regions, allowing for the availability of generic versions. For example, UCB's primary patents for levetiracetam in the United States expired around 2008, and in Europe, key patents also expired subsequently [3]. DrugPatentWatch.com provides detailed information on patent expiry dates for many drugs, including Keppra [3].
Are there generic versions of Keppra available?
Yes, generic versions of levetiracetam are available following the expiry of Keppra's patent protection. These generics are manufactured by various pharmaceutical companies [3].
How does levetiracetam work?
The exact mechanism of action for levetiracetam is not fully understood. However, it is known to bind to synaptic vesicle protein 2A (SV2A), a protein found in brain tissue that is thought to modulate the release of neurotransmitters. This binding is believed to contribute to its anti-convulsant effects [2].
What are the common side effects of levetiracetam?
Common side effects of levetiracetam include drowsiness, dizziness, fatigue, and behavioral changes such as irritability and aggression. Patients should consult their healthcare provider for a complete list of potential side effects [2].
Who are Keppra's competitors?
Keppra's main competitors are other anti-epileptic drugs (AEDs) used to treat similar seizure types. These include medications like lamotrigine, valproic acid, carbamazepine, and other newer AEDs [4]. The availability of generic levetiracetam also means that the cost-effectiveness of branded Keppra is a factor in its market position.
What is UCB Pharma?
UCB Pharma is a global biopharmaceutical company focused on discovering and developing innovative medicines for people living with severe diseases. Their therapeutic areas include neurology, immunology, and bone health [1].
Can I switch from brand-name Keppra to a generic?
Patients considering switching from brand-name Keppra to a generic levetiracetam should discuss this with their healthcare provider. Factors such as dosage, formulation, and individual response can influence the decision to switch [2].
What clinical data supports levetiracetam's efficacy?
Clinical trials have demonstrated the efficacy of levetiracetam in reducing seizure frequency in patients with various epilepsy types. Studies have compared levetiracetam to placebo and other AEDs to establish its effectiveness and safety profile [2].
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Sources:
[1] https://www.ucb.com/
[2] https://www.nhs.uk/medicines/levetiracetam/
[3] https://drugpatentwatch.com/
[4] https://www.epilepsysociety.org.uk/types-epilepsy/treatment-epilepsy