Advil is a brand name for ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, fever, and inflammation. However, like all NSAIDs, Advil can cause stomach ulcers and gastrointestinal bleeding [1]. According to the National Center for Biotechnology Information, NSAIDs can cause ulcers by reducing the production of prostaglandins, which are hormones that protect the stomach lining [2]. This can lead to the erosion of the stomach lining and the formation of ulcers.

In addition, long-term use of NSAIDs can increase the risk of developing stomach ulcers and gastrointestinal bleeding [2]. Therefore, it is important to use Advil as directed and to avoid taking it for extended periods without consulting a doctor. Patients who are at high risk of developing stomach ulcers, such as those with a history of ulcers or gastrointestinal bleeding, should avoid using Advil or other NSAIDs altogether.

If you experience symptoms such as abdominal pain, black or tarry stools, or vomiting blood while taking Advil, you should seek medical attention immediately [3]. These symptoms could indicate a serious gastrointestinal problem, such as a stomach ulcer or bleeding.

In conclusion, while Advil is an effective pain reliever, it can cause stomach ulcers and gastrointestinal bleeding, especially with long-term use. Patients should use Advil as directed and consult a doctor if they experience any symptoms of gastrointestinal problems while taking the medication. Patients at high risk of developing stomach ulcers should avoid using Advil or other NSAIDs altogether.

Sources:
[1] Drug Patent Watch. Advil. https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] National Center for Biotechnology Information. Ibuprofen. https://www.ncbi.nlm.nih.gov/books/NBK310269/
[3] GoodRx. Ibuprofen and Stomach Ulcers: Advil, Motrin. https://www.goodrx.com/ibuprofen/ibuprofen-stomach-ulcers-advil-motrin