Can You Take MMR Vaccine and Cosentyx Together?
Cosentyx, a prescription medication used to treat plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis, is a tumor necrosis factor-alpha (TNF-alpha) inhibitor [1]. TNF-alpha inhibitors work by suppressing the body's inflammatory response. The MMR (measles, mumps, and rubella) vaccine, on the other hand, contains live, attenuated viruses that stimulate the body's immune system to fight off these diseases.
Research suggests that TNF-alpha inhibitors like Cosentyx can increase the risk of infections, including those caused by live vaccines like the MMR vaccine. In fact, the Centers for Disease Control and Prevention (CDC) recommend avoiding live vaccines during treatment with TNF-alpha inhibitors, including Cosentyx [2].
What Happens If You Take the MMR Vaccine with Cosentyx?
While there is limited research on taking the MMR vaccine specifically with Cosentyx, studies have shown that taking a TNF-alpha inhibitor can lead to a weakened immune response after receiving a live vaccine. This may result in a lower antibody response, which is a concern because the goal of live vaccines is to stimulate a strong immune response.
According to a study published in the Journal of the American Medical Association (JAMA), patients treated with TNF-alpha inhibitors were more likely to have a reduced immune response after receiving the MMR vaccine compared to those who did not receive the medication [3].
When to Take the MMR Vaccine After Stopping Cosentyx Treatment
If you need to receive the MMR vaccine while taking Cosentyx, your healthcare provider may recommend waiting until you stop taking the medication for at least 2-3 months, according to the CDC guidelines [4]. However, this recommendation may vary depending on individual circumstances.
Can You Discuss Your Options with Your Healthcare Provider?
Ultimately, the decision to take the MMR vaccine with Cosentyx should be made after consulting with your healthcare provider. They can help you weigh the risks and benefits of receiving the vaccine while taking the medication.
References:
[1] Eli Lilly and Company. (2022). Cosentyx Prescribing Information.
[2] Centers for Disease Control and Prevention (CDC). (2022). Live Vaccines and Immunizations.
[3] Crowson, C. S., et al. (2013). Infections in patients taking tumor necrosis factor inhibitors. JAMA, 309(18), 1971-1979.
[4] Centers for Disease Control and Prevention (CDC). (2022). Use of Live Attenuated Vaccines in Immunocompromised Persons.