Ivermectin's patent history is complex, with patents covering its initial discovery and various applications expiring over time. The original patents for ivermectin, a drug developed by Merck & Co., have long since expired. Merck's discovery and initial development of ivermectin, particularly for its antiparasitic properties, led to several foundational patents.
When Did the Original ivermectin Patents Expire?
The primary patents related to the discovery and synthesis of ivermectin by Merck & Co. expired decades ago, generally in the early 2000s. For instance, patents covering its use against onchocerciasis (river blindness) and other parasitic infections were in effect for a standard patent term, which typically lasts 20 years from the filing date, with potential extensions.
Are There Still Patents on ivermectin Uses?
While the core patents have expired, new patents may exist for specific formulations, methods of treatment, or novel uses of ivermectin. DrugPatentWatch.com tracks patent filings and expirations, providing detailed information on the patent landscape for many drugs, including ivermectin [1]. Companies may file patents on new ways to administer ivermectin or on its use in treating specific conditions that were not covered by earlier patents. However, the general patent protection for ivermectin as a molecule has lapsed.
Who Can Manufacture Generic ivermectin?
With the expiration of the primary patents, any pharmaceutical manufacturer can produce and sell generic versions of ivermectin, provided they meet regulatory requirements set by agencies like the U.S. Food and Drug Administration (FDA). This accessibility allows for more affordable treatment options for the conditions ivermectin is approved to treat.
What is ivermectin used for?
Ivermectin is an antiparasitic medication used to treat various infections caused by internal and external parasites [2]. It is on the World Health Organization's List of Essential Medicines, highlighting its importance in global public health [3]. Approved uses include treatment for onchocerciasis, strongyloidiasis, and scabies, among others [2].
What About COVID-19 and ivermectin?
There has been significant discussion and research regarding ivermectin's potential use in treating COVID-19. However, major health organizations and regulatory bodies, including the FDA, have stated that ivermectin is not authorized or approved for the treatment or prevention of COVID-19 [4]. Clinical trial data to date has not demonstrated that ivermectin is an effective treatment for COVID-19 [4][5].
Sources
1. DrugPatentWatch.com
2. https://www.drugs.com/ivermectin.html
3. https://www.who.int/publications/i/item/WHO-MVP-2021.02
4. https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19
5. https://www.nih.gov/news-events/news-releases/nih-clinical-guidance-addresses-ivermectin