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Wo2010/029082 alpelisib novartis patent?

See the DrugPatentWatch profile for alpelisib

Short answer:
Yes. WO2010/029082 is a WIPO (PCT) publication by Novartis that discloses alpelisib (BYL719) and related PI3K inhibitors. It forms the core of the Novartis alpelisib patent family and covers the chemical compounds (including BYL719), their pharmaceutically acceptable salts, compositions, and methods of use for treating diseases mediated by PI3K, notably cancer.

What’s typically in this publication (at a high level):
- A class of compounds that are selective PI3K inhibitors, with BYL719 (alpelisib) provided as an example.
- Definitions of the chemical scaffolds and substituents (often showing a “formula I” with variable R groups).
- Pharmaceutical compositions and dosage forms.
- Methods of use in treating PI3Kα-related conditions (e.g., cancers) by inhibiting PI3Kα.
- Examples, including preparation and sometimes biological/activity data for BYL719 and related analogs.
- Information on synthesis and how to make the compounds.

How to check the details yourself (recommended):
- View the full text and claims
- WIPO PATENTSCOPE: search for WO2010/029082. The claims define the scope (which compounds, salts, and uses are protected).
- Explore the patent family and status
- Google Patents or Espacenet: look up the family member patents (e.g., US, EP equivalents) to see the granted claims, continuations, and legal status.
- Check for term extensions or pediatric extensions that affect expiry.
- For a quick read
- In Google Patents, open WO2010/029082, then use the “Claims” tab to see exactly what is claimed (lead compound BYL719 is highlighted in the description and examples, but the precise claimed scope is in the claims section).

If you want, I can:
- Pull out a claim-by-claim summary for the main independent claim(s) and the most relevant dependent claims.
- Identify the exact US/EP family members and provide their grant dates and current status.
- Extract the key structural features of the disclosed compounds as they relate to BYL719.

Let me know which level of detail you need (claims only, chemical structure, or legal status in specific jurisdictions), and I’ll tailor the summary.



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