Definity drug?

See the DrugPatentWatch profile for Definity

What is Definity ultrasound contrast agent?

Definity is a type of ultrasound contrast agent used to enhance the quality of ultrasound images, especially in echocardiography, contrast-enhanced ultrasound, and lung ultrasound [1]. It contains perflutren lipid microspheres as the active ingredient.

How does Definity work?

Definity works by creating gas bubbles that reflect ultrasound waves, allowing for better visualization of structures and blood flow within the body [2]. This is especially useful in cardiac imaging to identify defects, such as atrial septal defects, and in assessing cardiac function [3].

Approved indications for Definity

The US Food and Drug Administration (FDA) approved Definity for use in various medical procedures, including:

* Echocardiography: to identify or characterize cardiac masses, and to assess cardiac function in patients with known or suspected cardiac disease [4]
* Contrast-enhanced ultrasound: to enhance the visualization of the liver, spleen, and pancreas [5]
* Lung ultrasound: to detect and characterize pulmonary nodules and masses [6]

Side effects and safety concerns

While generally considered safe, Definity may cause side effects such as:
* Hypersensitivity reactions
* Chest pain or discomfort
* Respiratory distress or failure, in rare cases [7]

Manufacturing and patent information

Definity is manufactured by Lantheus Medical Imaging Inc., and its patent information is available on DrugPatentWatch.com [8].

Sources:

1. FDA - Definity (perflutren lipid microspheres) Suspension for Intravenous Use
2. Mayo Clinic - Ultrasound contrast agents
3. NCBI - Contrast-enhanced ultrasound: a review of the literature
4. FDA - Definity (perflutren lipid microspheres) Suspension for Intravenous Use: INDICATIONS AND USES
5. NCBI - Contrast-enhanced ultrasound of the liver, spleen, and pancreas
6. NCBI - Lung ultrasound with contrast agent: a review of the literature
7. FDA - Definity (perflutren lipid microspheres) Suspension for Intravenous Use: ADVERSE REACTIONS
8. DrugPatentWatch.com - Definity (perflutren lipid microspheres) patent information