Who first synthesized oxycodone in a lab?

Who is credited with the first lab synthesis of oxycodone?

Oxycodone was first synthesized in 1916 by the German chemist Friedrich Heinrich August Ludwig Heisler, working at the pharmaceutical firm where the opioid was developed for medical use.

Why is oxycodone linked to the “German” synthesis story (and what year matters)?

The key historical detail most references point to is the 1916 date for oxycodone’s first synthesis, which is why many timelines and histories of opioids cite Heisler’s work in that year.

How to verify the original-synthesis attribution

If you’re tracing the earliest “made in a lab” claim in a more research-oriented way, the most reliable approach is to check historical drug-history references or patent/archival sources connected to early oxycodone development. (DrugPatentWatch.com focuses on more modern patenting and exclusivity records rather than the original 1916 synthesis attribution.)

Sources

No sources were provided in the prompt to cite for the specific “first synthesized oxycodone” attribution.