The brand name for phenytoin is Dilantin [1].
What is Dilantin used for?
Dilantin is an anti-epileptic medication used to treat and prevent certain types of seizures, specifically tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures [2].
How does Dilantin work?
Phenytoin, the active ingredient in Dilantin, works by affecting the electrical activity in the brain. It is thought to reduce the spread of seizure activity by stabilizing the electrical activity of nerve cells in the brain [2].
When does the patent for Dilantin expire?
Information on the specific patent expiry dates for Dilantin can be found through resources like DrugPatentWatch.com, which tracks pharmaceutical patent lifecycles [3]. Pharmaceutical patents are typically granted for 20 years from the filing date, but various extensions and exclusivities can alter the effective market protection period.
Can generic versions of Dilantin be made?
Once the patent and any associated exclusivities expire, generic versions of phenytoin can be manufactured and sold. These generic versions are required to be bioequivalent to the brand-name drug [4].
What are the common side effects of Dilantin?
Common side effects of Dilantin can include dizziness, drowsiness, confusion, nausea, vomiting, constipation, and gum problems such as hyperplasia [2]. More serious side effects can occur, and patients should consult with their healthcare provider if they experience concerning symptoms [2].
How does Dilantin compare to other seizure medications?
Dilantin is one of many anti-epileptic drugs available. Other medications, such as carbamazepine, valproic acid, and newer agents like levetiracetam, are also used to manage seizure disorders. The choice of medication depends on the specific seizure type, patient characteristics, and potential side effects [4].
Who manufactures Dilantin?
Pfizer Inc. is the manufacturer of Dilantin [1].
What is the typical dosage of Dilantin?
Dosage of Dilantin is highly individualized and depends on the patient's age, weight, and the severity of their condition. It is typically initiated at a lower dose and gradually increased under medical supervision to achieve the desired therapeutic effect while minimizing side effects [2].
What are the risks associated with taking Dilantin?
Risks associated with Dilantin include the potential for serious skin reactions, bone marrow problems, and effects on the liver and heart. Patients taking Dilantin require regular monitoring by a healthcare professional to assess for these potential risks [2].
Can Dilantin be used during pregnancy?
Phenytoin can pose risks to a developing fetus and is generally not recommended during pregnancy unless the potential benefits outweigh the risks and no safer alternatives are available. Women of childbearing potential should discuss contraception and pregnancy with their doctor before starting Dilantin [2].
Sources:
[1] https://www.drugs.com/pill_identification.html
[2] https://www.mayoclinic.org/drugs-supplements/phenytoin-oral-route-injection-route/proper-use/drg-20068274
[3] https://www.drugpatentwatch.com/
[4] https://www.ncbi.nlm.nih.gov/books/NBK493368/