How to Use Gvoke for Severe Hypoglycemia
Gvoke (glucagon injection) treats severe low blood sugar (hypoglycemia) when someone is unconscious, can't swallow, or won't eat. It's for emergencies only, like blood sugar below 54 mg/dL with symptoms such as confusion, seizures, or fainting. Administer immediately if the person can't consume fast-acting carbs like juice or glucose tabs.1
Step-by-Step Instructions for Gvoke HypoPen (Prefilled Autoinjector)
- Check the dose: Use the 1 mg pen for adults and kids 12+; 0.5 mg for kids 2-12 (under 2 requires different formulation).
- Remove cap: Pull off the gray cap with one hand while holding the pen.
- Inject: Press the pen firmly against the thigh (through clothing if needed) for 5 seconds. Hold steady until the dose is delivered.
- Dispose: Put the used pen in a sharps container.
- Aftercare: Blood sugar should rise in 15 minutes. If no improvement, give another dose after 15 minutes. Once alert, feed carbs and monitor for 3+ hours.1
Using Gvoke PFS (Prefilled Syringe)
- Flip open lid and tear pouch.
- Screw syringe into the provided plunger.
- Inject: Insert needle into thigh muscle at 90 degrees, push plunger fully.
- Follow same aftercare as above.1
What Happens After Injection
Glucagon raises blood sugar by prompting the liver to release stored glucose, typically within 10-15 minutes. Call 911 after use, especially if first-time or no response. Side effects include nausea, vomiting; rare allergic reactions need immediate care.1
Common Mistakes to Avoid
Don't use if allergic to glucagon. Skip IV if untrained. Not for mild lows—use oral glucose first. Store at room temp (68-77°F); discard if expired or discolored.1
Who Can Administer and Training
Trained caregivers or patients (if able) can use it. Prescribe with glucagon training; many get it via prescription for home emergency kits.3
When to Seek Alternatives
If Gvoke unavailable, Baqsimi (nasal glucagon) or emergency glucose gel works similarly. Consult doctor for personalized plan.1
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