Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood and reduce the risk of heart attack and stroke [1]. Like all medications, it can cause side effects, and some of these can affect the liver.

According to the Mayo Clinic [2], liver problems are rare but possible side effects of Lipitor. The most common liver-related side effect is an increase in liver enzymes, which can indicate inflammation or damage to the liver. In rare cases, Lipitor can cause more serious liver problems, such as hepatitis or liver failure. Symptoms of liver problems can include fatigue, loss of appetite, abdominal pain, dark urine, and yellowing of the skin and eyes (jaundice).

DrugWatch [3] also notes that Lipitor can cause muscle damage (myopathy), which can affect the liver because damaged muscle tissue releases enzymes that can be harmful to the liver. Symptoms of myopathy can include muscle pain, weakness, and tenderness.

It is important to note that liver problems are rare side effects of Lipitor, and most people who take the medication do not experience any liver-related side effects. However, if you experience any symptoms of liver problems while taking Lipitor, you should contact your doctor right away.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013
[3] https://www.drugwatch.com/lipitor/side-effects/