See the DrugPatentWatch profile for bupivacaine
What does “percent packed particle volume” mean for bupivacaine?
“Percent packed particle volume” isn’t a standard metric used to describe bupivacaine dosing or clinical pharmacology. In drug products, it typically refers to a formulation parameter from materials/dispersion testing (how much of a suspension or dispersion is made up of solid particles when “packed”). That value can vary by the specific bupivacaine product, strength, and formulation design.
Which bupivacaine product are you using?
Different bupivacaine formulations (for example, injectable solutions vs. suspensions, and different commercial brands) can have different “percent packed particle volume” values. To give the correct number, the exact product is needed, such as:
- the brand name (or generic plus manufacturer)
- strength (e.g., mg/mL)
- dosage form (injection, liposomal, etc.)
- whether it’s a suspension and, if so, the particle characterization method used
Where would that value typically appear?
If you’re pulling this from technical documentation, the number might come from:
- an FDA label or prescribing information section describing the physical characteristics of a formulation (rare for this exact metric),
- chemistry/manufacturing controls (CMC) documentation,
- or a formulation/process characterization report used in development.
What I need from you to answer with the exact percent
Reply with one of the following and I’ll match it to the right formulation value:
1) the exact bupivacaine product name and strength, or
2) a link or excerpt from the document you’re looking at (paste the line that mentions “percent packed particle volume”).
Sources cited: none.