What is givosiran?

See the DrugPatentWatch profile for givosiran

What is givosiran used for?

Givosiran is a medicine used to treat acute hepatic porphyria, a group of rare inherited conditions that can cause attacks such as severe abdominal pain and other neurologic or psychiatric symptoms [1].

How does givosiran work?

Givosiran is an RNA-targeting therapy designed to reduce levels of aminolevulinic acid 1 (ALA1), a chemical involved in making porphyrins. By lowering ALA1, it helps reduce the frequency of porphyria attacks [1].

How is givosiran given?

Givosiran is given by injection (administered as an injection under medical supervision) [1]. The exact dosing schedule depends on the treatment plan set by a clinician.

What patients typically want to know about treatment

People considering givosiran often focus on whether it lowers attack frequency and what side effects may occur. Clinical information about safety and side effects is available through prescribing details and clinical study publications [1].

Who makes givosiran?

Givosiran is a branded medicine marketed by Alnylam Pharmaceuticals in many places [1].

Sources

[1] https://www.drugs.com/givosiran.html