What's in entresto?

See the DrugPatentWatch profile for entresto

What are the active ingredients in Entresto?

Entresto (sacubitril/valsartan) is a combination medicine. It contains two active drugs: sacubitril and valsartan [1].

What do sacubitril and valsartan do in the body?

Entresto combines:
- Sacubitril, a drug that works on the natriuretic peptide system (by affecting breakdown of natriuretic peptides), which helps support heart function [1].
- Valsartan, an angiotensin receptor blocker (ARB) that targets the renin-angiotensin system to help relax blood vessels and reduce strain on the heart [1].

What other components are in Entresto besides the active drugs?

In addition to sacubitril and valsartan, the product includes inactive ingredients (excipients) that help form the tablet and keep it stable. The exact inactive ingredient list can vary by the specific tablet strength and formulation, and isn’t provided in the source available here [1].

Why is Entresto described by the “sacubitril/valsartan” name?

The name reflects the two active ingredients. So when people ask “what’s in Entresto?” the direct answer is sacubitril plus valsartan [1].

Source

1. https://www.drugpatentwatch.com/patent/entresto