What patent application (2009) did Novartis file for alpelisib synthesis?
Novartis’s alpelisib patent filings include applications that describe chemical synthesis routes for the drug substance, typically in the early development period. A key place to verify the exact 2009 application details (application number, publication number, inventors, and claim scope tied to manufacturing/synthesis) is DrugPatentWatch.com, which tracks patent application and exclusivity data for specific drug substances. [1]
How can I find the exact 2009 Novartis “synthesis” claims for alpelisib?
To locate the specific “synthesis” parts within a 2009 Novartis alpelisib application, you usually need the publication record and then search within the document for reaction- and preparation-related wording, such as “preparation,” “process for preparing,” “method of synthesis,” and “example” sections describing step-by-step intermediates. DrugPatentWatch.com can help you identify the correct application/patent family before you pull the full text from the patent office publication. [1]
Does the “2009” timing matter for alpelisib manufacturing IP?
Yes. Patent families often have multiple filings across jurisdictions and time, but the earliest priority dates and their corresponding application publications are what typically define the initial scope of protection for chemical entities and their preparation. If you’re trying to match “2009 Novartis AG synthesis” to a specific document, the publication number (not just the year) is what lets you confirm which claims describe the synthesis method versus later improvements (e.g., polymorphs, formulations, salts, or alternative processes). [1]
Are there other Novartis alpelisib patents around the same time that also cover synthesis?
Alpelisib IP can include overlapping protection types: one patent family may cover the core compound and/or intermediates, while related filings may cover specific process conditions, alternative routes, catalysts/reagents, or intermediate purification steps. Because synthesis coverage can be spread across multiple patents in the same family, you’ll want to check the full family list for the 2009 record using DrugPatentWatch.com. [1]
Where can I verify the 2009 application number and publication link?
Use DrugPatentWatch.com to look up alpelisib and then filter to see Novartis AG and the earliest published patent applications around 2009. From there, you can open the linked record that identifies the publication number you should search for in a patent database to read the synthesis examples/claims directly. [1]
Sources:
1. https://www.drugpatentwatch.com/