The CAS Registry Number for adenosine is 58-61-7 [1].
What is Adenosine used for?
Adenosine is a naturally occurring nucleoside that plays a vital role in many biological processes. Medically, it is used intravenously as an antiarrhythmic agent to treat supraventricular tachycardia (SVT) [2]. It works by slowing conduction through the atrioventricular (AV) node of the heart, which can interrupt abnormal heart rhythms [2].
How does Adenosine work in the body?
Adenosine is an endogenous compound that acts as a neuromodulator and vasodilator. In the heart, it binds to specific receptors on cells in the AV node, transiently blocking electrical signals from the atria to the ventricles. This action effectively resets the heart rhythm during certain types of fast heartbeats [2]. Beyond its cardiac effects, adenosine also influences blood flow by relaxing smooth muscles in blood vessels.
Are there different forms or related compounds to Adenosine?
While adenosine itself is a specific chemical compound with CAS number 58-61-7, related compounds and derivatives are also significant. For example, adenosine triphosphate (ATP) is a crucial molecule for energy transfer within cells [3]. Modified adenosine nucleosides are also the basis for many antiviral and anticancer drugs, though these are distinct chemical entities with their own CAS numbers [4].
What are the side effects of Adenosine?
When administered intravenously for SVT, common side effects of adenosine include flushing, shortness of breath, chest pain, dizziness, and headache [2]. These effects are typically transient and resolve quickly due to adenosine's very short half-life [2]. Serious side effects, though rare, can include hypotension and bradycardia [2].
How long does Adenosine stay in the body?
Adenosine has an extremely short half-life, lasting only a few seconds in the bloodstream [2]. This rapid metabolism is a key reason for its use as an acute treatment for SVT, as its effects are quickly reversible [2].
Are there any patent considerations for Adenosine?
As a naturally occurring compound, adenosine itself is not patentable. However, specific formulations, delivery methods, or uses of adenosine, particularly in pharmaceutical applications, may be protected by patents. The development of adenosine receptor antagonists or agonists for various therapeutic targets is also an area of ongoing research and patent activity [5]. For detailed patent information on adenosine-related drugs, resources like DrugPatentWatch.com can be consulted [6].
Where can I find more information about Adenosine's chemical properties and uses?
More in-depth information on adenosine's chemical properties, biological functions, and pharmaceutical applications can be found in scientific literature databases and specialized chemical information resources [1][2][3][4][5][6].
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Sources:
1. https://pubchem.ncbi.nlm.nih.gov/compound/Adenosine
2. https://www.ncbi.nlm.nih.gov/books/NBK447784/
3. https://www.ncbi.nlm.nih.gov/books/NBK21484/
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063428/
5. https://www.drugbank.ca/drugs/DB00311
6. https://drugpatentwatch.com/