What is the Skyrizi (risankizumab) loading dose schedule?
Skyrizi uses an injection schedule that includes an initial “loading” phase before moving to less frequent maintenance dosing. After the first doses, you take it once every 8 weeks [1].
How often do you take Skyrizi in the first few months?
Common dosing is:
- Week 0: 150 mg (two 75 mg injections)
- Week 4: 150 mg (two 75 mg injections)
- Week 8 and onward: 150 mg every 8 weeks [1]
What if you miss a Skyrizi dose?
The prescribing information outlines guidance for missed doses, but the right step depends on how far you are from the next scheduled injection. If you tell me whether you’re early/late relative to your Week 0/4/8 plan, I can help map the schedule to that scenario using the product guidance [1].
Is the loading-dose schedule the same for all Skyrizi uses?
Skyrizi’s dosing schedule depends on the condition being treated. The loading-dose schedule above is the standard schedule listed for plaque psoriasis dosing in the US label [1]. If you’re asking for psoriatic arthritis, Crohn’s disease, or another indication, share the condition and I’ll align the schedule to that use.
Where is the loading-dose schedule documented?
The dosing and injection frequency (Week 0, Week 4, then every 8 weeks starting Week 8) are described in Skyrizi’s prescribing information [1].
Sources
[1] https://www.accessdata.fda.gov/drugsatfda_docs/label/